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This record was downloaded 0 times by a user of the Tivatrainerİ simulation program
Uploaded by on 2016-04-05 at 11:04:49

Name

Propofol

Description

Obese (pooled)

Author

Cortinez

Publication

British Journal of Anaesthesia 105 (4): 448-56 (2010)

Drug Type

Hypnotics

Co-parameters

Age, TBW allometric

Dilution (mg/ml)

Manual Bolus Units

mg/kg

Manual Rate Units

mg/kg/hr

Opioid Potency

-1

Limitations

{Age<25|Age too low}{Age>85|Age too high}

Kinetic Parameter Type

Clearances

 

 

VC

K12 or C2 or ThAlfa

1.45*((Weight/70)^0.75)*(2.71828182845904^((age*-0.0153)-(50*-0.0153)))

K21 or V2 or ThBheta

21.2*(weight/70)*(2.71828182845904^((age*-0.0164)-(50*-0.0164)))

K13 or C3 or ThGamma

0.86*((Weight/70)^0.75)

K31 or V3 or Vdss

K10 or Clearance

1.92*((weight/70)^0.75)

Thalf Keo

Effect label

Thalf Keo extra

Effect label extra

Cp low

Hint Cp low

Cp high

5000

Hint Cp high

Hint Area

Cp watch

Max Y

10000

Decimals

Tick Y axis

1000

Max Y rate

1000

Concentration units

µg

Scaling factor

1000

Overshoot (Effect TCI)

{Age<55|110+(5-asa)*35}{Age>90|110}{Age>55|110+(5-ASA)*(90-Age)}

Record edited by:

Frank Engbers

Version

1